Proquazone

Nonsteroidal anti-inflammatory drug From Wikipedia, the free encyclopedia

Proquazone is a nonsteroidal anti-inflammatory drug, known as an NSAID.[1]

ATC code
CAS Number
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Proquazone
Clinical data
ATC code
Identifiers
  • 1-isopropyl-7-methyl-4-phenylquinazolin-2(1H)-one
CAS Number
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ChEMBL
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ECHA InfoCard100.041.079 Edit this at Wikidata
Chemical and physical data
FormulaC18H18N2O
Molar mass278.355 g·mol−1
3D model (JSmol)
  • CC1=CC2=C(C=C1)C(=NC(=O)N2C(C)C)C3=CC=CC=C3
  • InChI=1S/C18H18N2O/c1-12(2)20-16-11-13(3)9-10-15(16)17(19-18(20)21)14-7-5-4-6-8-14/h4-12H,1-3H3 ☒N
  • Key:JTIGKVIOEQASGT-UHFFFAOYSA-N ☒N
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Uses

Proquazone is used to treat rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.[1] It has been trialed for use as pain relief for tension headaches.[2]

The recommended adult dose is around 450mg.[1]

Side Effects

Often, use of Proquazone is associated with diarrhea (up to 30% of the time).[1]

References

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