RAB11FIP3

Rab11 family-interacting protein 3 is a protein that in humans is encoded by the RAB11FIP3 gene.^[5][6][7]

PDBOrtholog search: PDBe RCSB

AliasesRAB11FIP3, CART1, Rab11-FIP3, RAB11 family interacting protein 3, FIP3-Rab11

External IDsOMIM: 608738; MGI: 2444431; HomoloGene: 49396; GeneCards: RAB11FIP3; OMA:RAB11FIP3 - orthologs

Chr.Chromosome 16 (human)^[1]

Quick facts Available structures, PDB ...

RAB11FIP3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D7C, 2HV8, 4D0M, 4UJ3, 4UJ4
Identifiers
Aliases	RAB11FIP3, CART1, Rab11-FIP3, RAB11 family interacting protein 3, FIP3-Rab11
External IDs	OMIM: 608738; MGI: 2444431; HomoloGene: 49396; GeneCards: RAB11FIP3; OMA:RAB11FIP3 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 425,649 bp[1] End 523,011 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 26,208,010 bp[2] End 26,288,529 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell right hemisphere of cerebellum human kidney sural nerve renal medulla renal cortex visceral pleura right frontal lobe cingulate gyrus anterior cingulate cortex Top expressed in right kidney proximal tubule human kidney knee joint muscle of thigh dentate gyrus of hippocampal formation granule cell primary visual cortex superior frontal gyrus skeletal muscle tissue neural layer of retina More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding protein homodimerization activity metal ion binding protein binding dynein light intermediate chain binding Cellular component cytoplasm recycling endosome cytosol endosome centrosome intracellular membrane-bounded organelle membrane nucleoplasm microtubule organizing center recycling endosome membrane midbody intercellular bridge cleavage furrow cytoskeleton endocytic vesicle Biological process cell division endocytic recycling cell cycle negative regulation of adiponectin secretion vesicle-mediated transport cytokinesis regulation of cytokinesis protein localization to cilium Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9727 215445 Ensembl ENSG00000090565 ENSG00000275338 ENSMUSG00000037098 UniProt O75154 Q8CHD8 RefSeq (mRNA) NM_001142272 NM_014700 NM_001370401 NM_001162868 NM_001162869 NM_153140 RefSeq (protein) NP_001135744 NP_055515 NP_001357330 NP_001156340 NP_001156341 NP_694780 Location (UCSC) Chr 16: 0.43 – 0.52 Mb Chr 17: 26.21 – 26.29 Mb PubMed search [3] [4]
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Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001).[supplied by OMIM]^[7]