RAB2A

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Ras-related protein Rab-2A is a protein that in humans is encoded by the RAB2A gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesRAB2A, LHX, RAB2, member RAS oncogene family
Quick facts Available structures, PDB ...
RAB2A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRAB2A, LHX, RAB2, member RAS oncogene family
External IDsOMIM: 179509; MGI: 1928750; HomoloGene: 20628; GeneCards: RAB2A; OMA:RAB2A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002865
NM_001242644

NM_021518

RefSeq (protein)

NP_001229573
NP_002856

NP_067493

Location (UCSC)Chr 8: 60.52 – 60.62 MbChr 4: 8.54 – 8.61 Mb
PubMed search[3][4]
Wikidata
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Function

Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rabs are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking. The mammalian RAB proteins show striking similarities to the S. cerevisiae YPT1 and SEC4 proteins, Ras-related GTP-binding proteins involved in the regulation of secretion.[supplied by OMIM][5]

Interactions

RAB2A has been shown to interact with GOLGA2.[6][7]

References

Further reading

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