RAET1E

RAET1E
Identifiers
Aliases	RAET1E, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4, bA350J20.7, retinoic acid early transcript 1E
External IDs	OMIM: 609243; HomoloGene: 131086; GeneCards: RAET1E; OMA:RAET1E - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	149,898,113 bp
RNA expression pattern
	Top expressed in
	mucosa of esophagus; ; zone of skin; ; skin of abdomen; ; skin of leg; ; vagina; ; testicle; ; olfactory zone of nasal mucosa; ; Achilles tendon; ; tonsil; ; gonad;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	natural killer cell lectin-like receptor binding; protein binding;
Cellular component	integral component of membrane; extracellular region; plasma membrane; membrane; extracellular space; external side of plasma membrane;
Biological process	T cell mediated cytotoxicity; natural killer cell mediated cytotoxicity; regulation of immune response; immune system process; positive regulation of natural killer cell mediated cytotoxicity; immune response; natural killer cell activation; susceptibility to natural killer cell mediated cytotoxicity;
	Sources:Amigo / QuickGO
Orthologs
	135250
	n/a
	ENSG00000164520
	n/a
	Q8TD07
	n/a
NM_001243325; NM_001243327; NM_001243328; NM_139165; NM_001394056;
	NM_001394057
	n/a
	NP_001230254; NP_001230256; NP_001230257; NP_631904
	n/a
	Wikidata
View/Edit Human

Retinoic acid early transcript 1E (RAET1E) is a cell surface glycoprotein encoded by RAET1E gene located on the chromosome 6.^[3] RAET1E is related to MHC class I molecules, but its gene maps outside the MHC locus.^[3] RAET1E is composed of external α1α2 domain, transmembrane segment and C-terminal cytoplasmic tail.^[3]^[4] RAET1E functions as a stress-induced ligand for NKG2D receptor.^[4]