RAP1B

RAP1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3BRW, 3CF6, 4DXA, 4HDO, 4HDQ, 4M8N, 4MGI, 4MGK, 4MGY, 4MGZ, 4MH0
Identifiers
Aliases	RAP1B, K-REV, RAL1B, member of RAS oncogene family
External IDs	OMIM: 179530; MGI: 894315; HomoloGene: 68719; GeneCards: RAP1B; OMA:RAP1B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	68,671,901 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	117,681,940 bp
RNA expression pattern
	Top expressed in
	monocyte; ; Achilles tendon; ; lymph node; ; granulocyte; ; appendix; ; endometrium; ; smooth muscle tissue; ; gonad; ; tibial arteries; ; bone marrow;
	Top expressed in
	left lung lobe; ; blood; ; decidua; ; stroma of bone marrow; ; right lung lobe; ; endocardial cushion; ; ureter; ; dermis; ; gastrula; ; endothelial cell of lymphatic vessel;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GDP binding; protein-containing complex binding; GTP binding; protein binding; GTPase activity;
Cellular component	cytoplasm; cytosol; membrane; cell-cell junction; plasma membrane; lipid droplet; intracellular anatomical structure; cell junction; membrane raft; extracellular exosome; azurophil granule membrane;
Biological process	establishment of endothelial barrier; microvillus assembly; regulation of cell junction assembly; Rap protein signal transduction; regulation of establishment of cell polarity; cellular response to cAMP; signal transduction; neutrophil degranulation; interleukin-12-mediated signaling pathway; small GTPase mediated signal transduction; cell population proliferation; response to carbohydrate; negative regulation of calcium ion-dependent exocytosis; positive regulation of ERK1 and ERK2 cascade; cellular response to organic cyclic compound; cellular response to gonadotropin-releasing hormone; negative regulation of synaptic vesicle exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	5908
	215449
	ENSG00000127314
	ENSMUSG00000052681
	P61224
	Q99JI6
NM_015646; NM_001010942; NM_001251917; NM_001251918; NM_001251921;
	NM_001251922
	NM_024457
NP_001010942; NP_001238846; NP_001238847; NP_001238850; NP_001238851;
	NP_056461; NP_001010942.1; NP_056461.1
	NP_077777
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, is a protein that in humans is encoded by the RAP1B gene.^[5]^[6]^[7]^[8]