RBMX

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Heterogeneous nuclear ribonucleoprotein G is a protein that in humans is encoded by the RBMX gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesRBMX, HNRNPG, HNRPG, RBMXP1, RBMXRT, RNMX, hnRNP-G, MRXS11, RNA binding motif protein, X-linked, RNA binding motif protein X-linked
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RBMX
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRBMX, HNRNPG, HNRPG, RBMXP1, RBMXRT, RNMX, hnRNP-G, MRXS11, RNA binding motif protein, X-linked, RNA binding motif protein X-linked
External IDsOMIM: 300199; MGI: 1343044; HomoloGene: 20494; GeneCards: RBMX; OMA:RBMX - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001164803
NM_002139

NM_001166623
NM_011252

RefSeq (protein)

NP_001158275
NP_002130

NP_001160095
NP_035382

Location (UCSC)Chr X: 136.85 – 136.88 MbChr X: 56.43 – 56.44 Mb
PubMed search[3][4]
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Function

This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified but their biological nature has not been determined.[7]

Interactions

RBMX has been shown to interact with SFRS10[8] and CDC5L.[9]

References

Further reading

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