RCC2

RCC2
Identifiers
Aliases	RCC2, TD-60, regulator of chromosome condensation 2
External IDs	OMIM: 609587; MGI: 1919784; HomoloGene: 10282; GeneCards: RCC2; OMA:RCC2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	17,439,677 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	140,450,531 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; lymph node; ; monocyte; ; skin of abdomen; ; stromal cell of endometrium; ; ventricular zone; ; skin of leg; ; appendix; ; granulocyte; ; gonad;
	Top expressed in
	ventricular zone; ; primitive streak; ; somite; ; epiblast; ; thymus; ; abdominal wall; ; fetal liver hematopoietic progenitor cell; ; ganglionic eminence; ; medial ganglionic eminence; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein domain specific binding; microtubule binding; small GTPase binding; protein binding; protein kinase binding; RNA binding; guanyl-nucleotide exchange factor activity;
Cellular component	cytoplasm; cytosol; early endosome membrane; membrane; plasma membrane; spindle; chromosome, centromeric core domain; chromosome; mitotic spindle midzone; midbody; nucleolus; microtubule; chromosome, centromeric region; cytoskeleton; nucleus;
Biological process	regulation of cell migration; activation of GTPase activity; establishment of protein localization; cell division; chromosome passenger complex localization to kinetochore; positive regulation of attachment of spindle microtubules to kinetochore; focal adhesion assembly; negative regulation of GTPase activity; regulation of ruffle assembly; integrin-mediated signaling pathway; positive regulation of G2/M transition of mitotic cell cycle; cell cycle; negative regulation of substrate adhesion-dependent cell spreading; regulation of fibroblast migration; negative regulation of focal adhesion assembly; sister chromatid cohesion;
	Sources:Amigo / QuickGO
Orthologs
	55920
	108911
	ENSG00000281540; ENSG00000179051
	ENSMUSG00000040945
	Q9P258
	Q8BK67
	NM_018715; NM_001136204
	NM_173867
	NP_001129676; NP_061185; NP_001129676.1; NP_061185.1
	NP_776292
	Wikidata
View/Edit Human	View/Edit Mouse

Protein RCC2 also known as telophase disk protein of 60 kDa (TD-60) or RCC1-like protein TD-60 is a protein that in humans is encoded by the RCC2 gene.^[5]^[6]^[7]