REXO2

Protein-coding gene in humans From Wikipedia, the free encyclopedia

REX2, RNA exonuclease 2 homolog (S. cerevisiae), also known as REXO2, is an enzyme which in humans is encoded by the REXO2 gene.[5][6][7]

AliasesREXO2, REX2, RFN, SFN, CGI-114, RNA exonuclease 2
End114,450,279 bp[1]
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REXO2
Identifiers
AliasesREXO2, REX2, RFN, SFN, CGI-114, RNA exonuclease 2
External IDsOMIM: 607149; MGI: 1888981; HomoloGene: 6447; GeneCards: REXO2; OMA:REXO2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015523

NM_024233
NM_001357501
NM_001357503
NM_001357505

RefSeq (protein)

NP_056338

NP_077195
NP_001344430
NP_001344432
NP_001344434

Location (UCSC)Chr 11: 114.44 – 114.45 MbChr 9: 48.38 – 48.39 Mb
PubMed search[3][4]
Wikidata
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Function

Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mono-nucleotides in a sequential manner.[5]

References

Further reading

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