RFWD2

COP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5IGQ, 5HQG
Identifiers
Aliases	COP1, RNF200, ring finger and WD repeat domain 2, E3 ubiquitin ligase, RFWD2, COP1 E3 ubiquitin ligase, FAP78, CFAP78
External IDs	OMIM: 608067; MGI: 1347046; HomoloGene: 115565; GeneCards: COP1; OMA:COP1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	176,207,286 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	159,175,210 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; mucosa of transverse colon; ; ganglionic eminence; ; blood; ; ventricular zone; ; gonad; ; white blood cell; ; monocyte; ; bone marrow cell; ; skin of arm;
	Top expressed in
	zygote; ; tail of embryo; ; genital tubercle; ; granulocyte; ; ventricular zone; ; muscle of thigh; ; spermatocyte; ; esophagus; ; dentate gyrus of hippocampal formation granule cell; ; spermatid;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; metal ion binding; ubiquitin-protein transferase activity; transferase activity; ubiquitin protein ligase activity; zinc ion binding;
Cellular component	nuclear speck; cytosol; Golgi membrane; nucleus; cytoplasm; nucleoplasm; Cul4A-RING E3 ubiquitin ligase complex; centrosome; focal adhesion;
Biological process	protein ubiquitination; response to ionizing radiation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; post-translational protein modification; proteasome-mediated ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	64326
	26374
	ENSG00000143207
	ENSMUSG00000040782
	Q8NHY2
	Q9R1A8
	NM_001001740; NM_001286644; NM_022457
	NM_011931; NM_001360878
	NP_001001740; NP_001273573; NP_071902
	NP_036061; NP_001347807
	Wikidata
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