RNF11

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

RING finger protein 11 is a protein that in humans is encoded by the RNF11 gene.[5][6][7]

AliasesRNF11, SID1669, CGI-123, ring finger protein 11
End51,273,447 bp[1]
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RNF11
Identifiers
AliasesRNF11, SID1669, CGI-123, ring finger protein 11
External IDsOMIM: 612598; MGI: 1352759; HomoloGene: 32195; GeneCards: RNF11; OMA:RNF11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014372

NM_013876

RefSeq (protein)

NP_055187

NP_038904

Location (UCSC)Chr 1: 51.24 – 51.27 MbChr 4: 109.31 – 109.34 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN).[7]

See also

Interactions

RNF11 has been shown to interact with RIPK1[8] and STAMBP.[9]

References

Further reading

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