60S ribosomal protein L31

Protein found in humans From Wikipedia, the free encyclopedia

60S ribosomal protein L31 is a protein that in humans is encoded by the RPL31 gene.[5][6][7]

Quick facts RPL31, Identifiers ...
RPL31
Identifiers
AliasesRPL31, L31, ribosomal protein L31
External IDsOMIM: 617415; MGI: 2149632; HomoloGene: 133014; GeneCards: RPL31; OMA:RPL31 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001099693
NM_000993
NM_001098577

NM_001252218
NM_001252219
NM_053257

RefSeq (protein)

n/a

NP_001239147
NP_001239148
NP_444487

Location (UCSC)Chr 2: 101 – 101.02 MbChr 1: 39.41 – 39.41 Mb
PubMed search[3][4]
Wikidata
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Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L31E family of ribosomal proteins. It is located in the cytoplasm. Higher levels of expression of this gene in familial adenomatous polyps compared to matched normal tissues have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]

Interactions

RPL31 has been shown to interact with BRCA1.[8]

References

Further reading

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