40S ribosomal protein S15

40S ribosomal protein S15 is a protein that in humans is encoded by the RPS15 gene.^[5][6]

PDBOrtholog search: PDBe RCSB

AliasesRPS15, RIG, S15, ribosomal protein S15

External IDsOMIM: 180535; MGI: 98117; HomoloGene: 110643; GeneCards: RPS15; OMA:RPS15 - orthologs

Chr.Chromosome 19 (human)^[1]

Quick facts RPS15, Available structures ...

RPS15
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 5AJ0, 5FLX, 3J7R, 4D61, 4UJC, 4D5L, 4UJE, 3J7P, 4V5Z, 4UJD
Identifiers
Aliases	RPS15, RIG, S15, ribosomal protein S15
External IDs	OMIM: 180535; MGI: 98117; HomoloGene: 110643; GeneCards: RPS15; OMA:RPS15 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.3 Start 1,438,358 bp[1] End 1,440,495 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 C1 Start 80,128,287 bp[2] End 80,129,948 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pituitary gland anterior pituitary right hemisphere of cerebellum skin of abdomen skin of leg left ovary right ovary prostate right uterine tube amygdala Top expressed in efferent ductule transitional epithelium of urinary bladder internal carotid artery abdominal wall medial ganglionic eminence mesenteric lymph nodes maxillary prominence migratory enteric neural crest cell dermis cervix More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding structural constituent of ribosome protein binding RNA binding Cellular component cytosol ribosome membrane focal adhesion cytosolic small ribosomal subunit small ribosomal subunit nucleus nucleoplasm Biological process ribosomal small subunit export from nucleus viral transcription SRP-dependent cotranslational protein targeting to membrane osteoblast differentiation translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ribosomal small subunit biogenesis ribosomal small subunit assembly protein biosynthesis rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6209 20054 Ensembl ENSG00000115268 ENSMUSG00000063457 UniProt P62841 P62843 RefSeq (mRNA) NM_001018 NM_001308226 NM_009091 NM_001310726 RefSeq (protein) NP_001009 NP_001295155 NP_001297655 NP_033117 Location (UCSC) Chr 19: 1.44 – 1.44 Mb Chr 10: 80.13 – 80.13 Mb PubMed search [3] [4]
Wikidata
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]