40S ribosomal protein S2

The RPS2 gene is the gene which, in humans, encodes the 40S ribosomal protein S2.^[5][6]

PDBOrtholog search: PDBe RCSB

AliasesRPS2, LLREP3, S2, ribosomal protein S2

External IDsOMIM: 603624; MGI: 105110; HomoloGene: 37714; GeneCards: RPS2; OMA:RPS2 - orthologs

Chr.Chromosome 16 (human)^[1]

Quick facts RPS2, Available structures ...

RPS2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 5AJ0, 5FLX, 4D61, 4D5L, 4UJD, 4UJE, 4UJC
Identifiers
Aliases	RPS2, LLREP3, S2, ribosomal protein S2
External IDs	OMIM: 603624; MGI: 105110; HomoloGene: 37714; GeneCards: RPS2; OMA:RPS2 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 1,962,058 bp[1] End 1,964,841 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 24,937,090 bp[2] End 24,940,903 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium right uterine tube right ovary body of pancreas left ovary ventricular zone mucosa of transverse colon ganglionic eminence granulocyte zone of skin Top expressed in ventricular zone lip esophagus ovary zone of skin lens ganglionic eminence ileum quadriceps femoris muscle uterus More reference expression data BioGPS n/a
Gene ontology Molecular function structural constituent of ribosome protein binding enzyme binding fibroblast growth factor binding mRNA binding RNA binding cadherin binding Cellular component cytosol ribosome membrane focal adhesion cytosolic small ribosomal subunit nucleolus small ribosomal subunit extracellular exosome nucleus nucleoplasm synapse Biological process viral transcription SRP-dependent cotranslational protein targeting to membrane translational initiation positive regulation of transferase activity nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein biosynthesis rRNA processing protein methylation positive regulation of ubiquitin-protein transferase activity cellular response to interleukin-4 Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6187 16898 Ensembl ENSG00000140988 ENSMUSG00000044533 UniProt P15880 P25444 RefSeq (mRNA) NM_002952 NM_008503 RefSeq (protein) NP_002943 NP_032529 Location (UCSC) Chr 16: 1.96 – 1.96 Mb Chr 17: 24.94 – 24.94 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S5P family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with mouse LLRep3. It is co-transcribed with the small nucleolar RNA gene U64, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]