40S ribosomal protein S28

40S ribosomal protein S28 is a protein that in humans is encoded by the RPS28 gene.^[5][6][7]

PDBOrtholog search: PDBe RCSB

AliasesRPS28, S28, DBA15, ribosomal protein S28, eS28

External IDsOMIM: 603685; MGI: 1859516; HomoloGene: 68150; GeneCards: RPS28; OMA:RPS28 - orthologs

Chr.Chromosome 19 (human)^[1]

Quick facts RPS28, Available structures ...

RPS28
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 5AJ0, 3J7P, 4KZX, 4UJE, 4KZY, 4D5L, 4KZZ, 3J7R, 4UJD, 5FLX, 4D61, 4UJC
Identifiers
Aliases	RPS28, S28, DBA15, ribosomal protein S28, eS28
External IDs	OMIM: 603685; MGI: 1859516; HomoloGene: 68150; GeneCards: RPS28; OMA:RPS28 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.2 Start 8,321,158 bp[1] End 8,323,340 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B1 Start 34,038,001 bp[2] End 34,043,536 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon anterior pituitary granulocyte stromal cell of endometrium skin of abdomen olfactory zone of nasal mucosa gonad right uterine tube body of pancreas left ovary Top expressed in yolk sac embryo embryo ventricular zone ganglionic eminence uterus bone marrow dentate gyrus of hippocampal formation granule cell blastocyst urinary bladder More reference expression data BioGPS n/a
Gene ontology Molecular function structural constituent of ribosome protein binding RNA binding Cellular component cytosol ribosome intracellular anatomical structure small ribosomal subunit extracellular exosome nucleoplasm cytosolic small ribosomal subunit cytoplasm endoplasmic reticulum rough endoplasmic reticulum polysomal ribosome cytoplasmic side of rough endoplasmic reticulum membrane Biological process ribosome biogenesis viral transcription SRP-dependent cotranslational protein targeting to membrane translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ribosomal small subunit biogenesis ribosomal small subunit assembly maturation of SSU-rRNA protein biosynthesis rRNA processing cytoplasmic translation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6234 54127 Ensembl ENSG00000233927 ENSMUSG00000067288 UniProt P62857 P62858 RefSeq (mRNA) NM_001031 NM_016844 NM_001355384 RefSeq (protein) NP_001022 NP_058540 NP_001342313 Location (UCSC) Chr 19: 8.32 – 8.32 Mb Chr 17: 34.04 – 34.04 Mb PubMed search [3] [4]
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S28E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[7]