RRM2

RRM2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2UW2, 3OLJ, 3VPM, 3VPN, 3VPO
Identifiers
Aliases	RRM2, R2, RR2, RR2M, ribonucleotide reductase regulatory subunit M2
External IDs	OMIM: 180390; MGI: 98181; HomoloGene: 20277; GeneCards: RRM2; OMA:RRM2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	10,211,725 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	24,764,145 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; ventricular zone; ; ganglionic eminence; ; trabecular bone; ; thymus; ; bone marrow; ; bone marrow cell; ; amniotic fluid; ; gingival epithelium; ; appendix;
	Top expressed in
	gastrula; ; decidua; ; fetal liver hematopoietic progenitor cell; ; somite; ; primitive streak; ; medial ganglionic eminence; ; tibiofemoral joint; ; abdominal wall; ; renal corpuscle; ; endothelial cell of lymphatic vessel;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding; oxidoreductase activity; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ferric iron binding; protein homodimerization activity;
Cellular component	cytoplasm; cytosol; ribonucleoside-diphosphate reductase complex;
Biological process	regulation of transcription involved in G1/S transition of mitotic cell cycle; deoxyribonucleotide biosynthetic process; DNA replication; negative regulation of G0 to G1 transition; deoxyribonucleotide metabolic process; protein complex oligomerization; protein heterotetramerization; nucleobase-containing small molecule interconversion;
	Sources:Amigo / QuickGO
Orthologs
	6241
	20135
	ENSG00000171848
	ENSMUSG00000020649
	P31350
	P11157
	NM_001165931; NM_001034
	NM_009104
	NP_001025; NP_001159403
	NP_033130
	Wikidata
View/Edit Human	View/Edit Mouse

Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2 gene.^[5]^[6]