RRP1

Ribosomal RNA processing protein 1 homolog A is a protein that in humans is encoded by the RRP1 gene.^[5][6][7]

AliasesRRP1, D21S2056E, NNP-1, NOP52, RRP1A, ribosomal RNA processing 1

External IDsOMIM: 610653; MGI: 1203500; HomoloGene: 90906; GeneCards: RRP1; OMA:RRP1 - orthologs

Chr.Chromosome 21 (human)^[1]

End43,805,293 bp^[1]

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RRP1
Identifiers
Aliases	RRP1, D21S2056E, NNP-1, NOP52, RRP1A, ribosomal RNA processing 1
External IDs	OMIM: 610653; MGI: 1203500; HomoloGene: 90906; GeneCards: RRP1; OMA:RRP1 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q22.3 Start 43,789,513 bp[1] End 43,805,293 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 C1|10 39.72 cM Start 78,236,218 bp[2] End 78,248,877 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii gingival epithelium skin of leg buccal mucosa cell skin of abdomen gastrocnemius muscle cerebellar vermis sural nerve prefrontal cortex ganglionic eminence Top expressed in dentate gyrus of hippocampal formation granule cell neural layer of retina superior frontal gyrus saccule primary visual cortex tail of embryo otic vesicle cerebellar cortex otic placode supraoptic nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding protein binding Cellular component nucleus nucleolus preribosome, small subunit precursor preribosome, large subunit precursor Biological process rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8568 18114 Ensembl ENSG00000160214 ENSMUSG00000061032 UniProt P56182 P56183 RefSeq (mRNA) NM_003683 NM_010925 RefSeq (protein) NP_003674 NP_035055 Location (UCSC) Chr 21: 43.79 – 43.81 Mb Chr 10: 78.24 – 78.25 Mb PubMed search [3] [4]
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The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA.^[7]