RSF1

Remodeling and spacing factor 1 is a protein that in humans is encoded by the RSF1 gene.^[5][6][7]

AliasesRSF1, HBXAP, RSF-1, XAP8, p325, remodeling and spacing factor 1

External IDsOMIM: 608522; MGI: 2682305; HomoloGene: 41142; GeneCards: RSF1; OMA:RSF1 - orthologs

Chr.Chromosome 11 (human)^[1]

End77,820,869 bp^[1]

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RSF1
Identifiers
Aliases	RSF1, HBXAP, RSF-1, XAP8, p325, remodeling and spacing factor 1
External IDs	OMIM: 608522; MGI: 2682305; HomoloGene: 41142; GeneCards: RSF1; OMA:RSF1 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q14.1 Start 77,660,009 bp[1] End 77,820,869 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 E1 Start 97,229,096 bp[2] End 97,341,985 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon internal globus pallidus sural nerve epithelium of colon tendon of biceps brachii cerebellar vermis Brodmann area 23 pars reticulata middle temporal gyrus external globus pallidus Top expressed in hand Rostral migratory stream tail of embryo genital tubercle ventromedial nucleus lateral septal nucleus otolith organ olfactory tubercle utricle maxillary prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function histone binding ATPase activity protein binding metal ion binding histone acetyltransferase activity Cellular component RSF complex nucleus nucleoplasm histone acetyltransferase complex Biological process positive regulation of transcription, DNA-templated negative regulation of DNA binding chromatin remodeling positive regulation of viral transcription negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated CENP-A containing chromatin assembly transcription, DNA-templated DNA-templated transcription, initiation nucleosome assembly chromatin organization histone acetylation positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51773 233532 Ensembl ENSG00000048649 ENSMUSG00000035623 UniProt Q96T23 Q05DG0 n/a RefSeq (mRNA) NM_016578 NM_001081267 RefSeq (protein) NP_057662 NP_057662.3 n/a Location (UCSC) Chr 11: 77.66 – 77.82 Mb Chr 7: 97.23 – 97.34 Mb PubMed search [3] [4]
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HBXAP is involved in transcription repression, transcription coactivation when associated with hepatitis B virus X protein (HBX), and chromatin remodeling and spacing when associated with SNF2H (MIM 603375).[supplied by OMIM]^[7]