RhoH

RHOH
Identifiers
Aliases	RHOH, ARHH, TTF, RhoH, ras homolog family member H
External IDs	OMIM: 602037; MGI: 1921984; HomoloGene: 3180; GeneCards: RHOH; OMA:RHOH - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	40,246,967 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	66,054,043 bp
RNA expression pattern
	Top expressed in
	bone marrow cell; ; lymph node; ; appendix; ; granulocyte; ; thymus; ; spleen; ; blood; ; epithelium of nasopharynx; ; tonsil; ; epithelium of colon;
	Top expressed in
	thymus; ; blood; ; mesenteric lymph nodes; ; spleen; ; primary oocyte; ; granulocyte; ; secondary oocyte; ; zygote; ; subcutaneous adipose tissue; ; bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	GTPase inhibitor activity; nucleotide binding; GTP binding; kinase inhibitor activity; protein binding; GTPase activity; protein kinase binding;
Cellular component	cytosol; plasma membrane; cytoplasm; membrane; immunological synapse; intracellular anatomical structure; cell cortex; cell projection;
Biological process	regulation of small GTPase mediated signal transduction; regulation of transcription, DNA-templated; negative regulation of I-kappaB kinase/NF-kappaB signaling; mast cell activation; T cell differentiation; negative regulation of phosphorylation; negative regulation of GTPase activity; small GTPase mediated signal transduction; actin filament organization; establishment or maintenance of cell polarity; Rho protein signal transduction; regulation of cell shape; actin cytoskeleton organization; negative regulation of kinase activity; regulation of actin cytoskeleton organization;
	Sources:Amigo / QuickGO
Orthologs
	399
	74734
	ENSG00000168421
	ENSMUSG00000029204
	Q15669
	Q9D3G9
NM_001278359; NM_001278360; NM_001278361; NM_001278362; NM_001278363;
	NM_001278364; NM_001278365; NM_001278366; NM_001278367; NM_001278368; NM_001278369; NM_004310
	NM_001081105; NM_001363454
NP_001265288; NP_001265289; NP_001265290; NP_001265291; NP_001265292;
	NP_001265293; NP_001265294; NP_001265295; NP_001265296; NP_001265297; NP_001265298; NP_004301
	NP_001074574; NP_001350383
	Wikidata
View/Edit Human	View/Edit Mouse

RhoH (Ras homolog gene family, member H) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases.^[5] It is encoded by the gene RHOH.^[6]