Ro 3-0422

Ro 3-0422
Names
	Preferred IUPAC name 3-[(Diethoxyphosphoryl)oxy]-1-methylquinolin-1-ium methyl sulfate
	Other names 3-(Diethoxyphosphinyloxy)-1-methylquinolinium methylsulfate
Identifiers
CAS Number	5823-09-6 ;
3D model (JSmol)	Interactive image;
ChemSpider	174347;
PubChem CID	201356;
UNII	C7KH7R89YX;
CompTox Dashboard (EPA)	DTXSID80206962 ;
	InChI InChI=1S/C14H19NO4P.CH4O4S/c1-4-17-20(16,18-5-2)19-13-10-12-8-6-7-9-14(12)15(3)11-13;1-5-6(2,3)4/h6-11H,4-5H2,1-3H3;1H3,(H,2,3,4)/q+1;/p-1 Key: YIGJQDOVGHXIJZ-UHFFFAOYSA-M;
	SMILES CCOP(=O)(OCC)Oc1cc2ccccc2[n+](c1)C.COS(=O)(=O)[O-];
Properties
Chemical formula	C15H22NO8PS
Molar mass	407.37 g·mol−1
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Extremely toxic
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	20 μg/kg (mice, intravenous)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Ro 3-0422 is an extremely potent organophosphate acetylcholinesterase inhibitor. It is extremely toxic. The intravenous LD₅₀ is 20 μg/kg in mice.^[1] It is over 300 times more potent than neostigmine.^[2]

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