SALL1

SALL1
Identifiers
Aliases	SALL1, HEL-S-89, HSAL1, Sal-1, TBS, ZNF794, spalt-like transcription factor 1, spalt like transcription factor 1
External IDs	OMIM: 602218; MGI: 1889585; HomoloGene: 2230; GeneCards: SALL1; OMA:SALL1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	51,152,334 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	89,770,790 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; inferior ganglion of vagus nerve; ; renal medulla; ; subthalamic nucleus; ; superior vestibular nucleus; ; ganglionic eminence; ; internal globus pallidus; ; stromal cell of endometrium; ; right lobe of liver; ; spinal cord;
	Top expressed in
	pineal gland; ; tail of embryo; ; ventricular zone; ; decidua; ; Rostral migratory stream; ; epiblast; ; olfactory bulb; ; primitive streak; ; renal corpuscle; ; gastrula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; beta-catenin binding; histone deacetylase activity; DNA-binding transcription factor activity; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; NuRD complex; nucleoplasm; heterochromatin; chromocenter; nucleus;
Biological process	neurogenesis; ureteric bud development; pituitary gland development; kidney epithelium development; inductive cell-cell signaling; regulation of transcription, DNA-templated; olfactory bulb mitral cell layer development; ventricular septum development; olfactory bulb interneuron differentiation; somatic stem cell population maintenance; kidney development; embryonic digit morphogenesis; mesenchymal to epithelial transition involved in metanephros morphogenesis; outer ear morphogenesis; olfactory nerve development; negative regulation of transcription by RNA polymerase II; adrenal gland development; ureteric bud invasion; transcription, DNA-templated; limb development; positive regulation of Wnt signaling pathway; positive regulation of transcription, DNA-templated; development of the heart; branching involved in ureteric bud morphogenesis; negative regulation of transcription, DNA-templated; gonad development; embryonic digestive tract development; positive regulation of transcription by RNA polymerase II; histone deacetylation;
	Sources:Amigo / QuickGO
Orthologs
	6299
	58198
	ENSG00000103449
	ENSMUSG00000031665
	Q9NSC2
	Q9ER74; Q6P5E3
	NM_001127892; NM_002968
	NM_021390; NM_001371069; NM_001371070
	NP_001121364; NP_002959
	NP_067365; NP_001357998; NP_001357999
	Wikidata
View/Edit Human	View/Edit Mouse

Sal-like 1 (Drosophila), also known as SALL1, is a protein which in humans is encoded by the SALL1 gene.^[5]^[6] As the full name suggests, it is one of the human versions of the spalt (sal) gene known in Drosophila.