SB-258719

SB-258719
Identifiers
	IUPAC name (1R)-3,N-dimethyl-N-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide;
CAS Number	195199-95-2 ;
PubChem CID	5312148;
IUPHAR/BPS	281;
ChemSpider	4471578 ;
UNII	GF43CP5LXQ;
ChEMBL	ChEMBL12264 ;
CompTox Dashboard (EPA)	DTXSID201029788 ;
Chemical and physical data
Formula	C18H30N2O2S
Molar mass	338.51 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1ccc(C)cc1S(=O)(=O)N(C)C(C)CCN(CC2)CCC2C;
	InChI InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1 ; Key:AGVNHDNTFYHZNL-QGZVFWFLSA-N ;
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SB-258719 is a drug developed by GlaxoSmithKline which acts as a selective 5-HT₇ receptor partial inverse agonist,^[1] and was the first such ligand identified for 5-HT₇.^[2] Its use in research has mainly been in demonstrating the potential use for 5-HT₇ agonists as potential novel analgesics, due to the ability of SB-258719 to block the analgesic effects of a variety of 5-HT₇ agonists across several different testing models.^[3]^[4]^[5]^[6]

CAS Number

195199-95-2^N

PubChem CID

5312148

IUPHAR/BPS

281

ChemSpider

4471578^Y

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SB-258719

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Identifiers

IUPAC name (1R)-3,N-dimethyl-N-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide
CAS Number	195199-95-2^N
PubChem CID	5312148
IUPHAR/BPS	281
ChemSpider	4471578^Y
UNII	GF43CP5LXQ
ChEMBL	ChEMBL12264^Y
CompTox Dashboard (EPA)	DTXSID201029788
Chemical and physical data
Formula	C₁₈H₃₀N₂O₂S
Molar mass	338.51 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c1ccc(C)cc1S(=O)(=O)N(C)C(C)CCN(CC2)CCC2C
InChI InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1^Y Key:AGVNHDNTFYHZNL-QGZVFWFLSA-N^Y
^NY (what is this?) (verify)