SC65
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Endoplasmic reticulum protein SC65, also known as Leprecan-like protein 4 (LEPREL4) or nucleolar autoantigen No55, is a protein that in humans is encoded by the P3H4 gene.[5]
AliasesP3H4, NO55, NOL55, SC65, LEPREL4, prolyl 3-hydroxylase family member 4 (non-enzymatic), prolyl 3-hydroxylase family member 4 (inactive)
External IDsOMIM: 617419; MGI: 1913430; HomoloGene: 4713; GeneCards: P3H4; OMA:P3H4 - orthologs
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| Aliases | P3H4, NO55, NOL55, SC65, LEPREL4, prolyl 3-hydroxylase family member 4 (non-enzymatic), prolyl 3-hydroxylase family member 4 (inactive) | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 617419; MGI: 1913430; HomoloGene: 4713; GeneCards: P3H4; OMA:P3H4 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.[5]
