SDK2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Protein sidekick-2 is a protein that in humans is encoded by the SDK2 gene.[5][6][7][8]

PDBOrtholog search: PDBe RCSB
AliasesSDK2, sidekick cell adhesion molecule 2
Quick facts Available structures, PDB ...
SDK2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSDK2, sidekick cell adhesion molecule 2
External IDsOMIM: 607217; MGI: 2443847; HomoloGene: 10406; GeneCards: SDK2; OMA:SDK2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001144952
NM_019064

NM_172800

RefSeq (protein)

NP_001138424

NP_766388

Location (UCSC)Chr 17: 73.33 – 73.64 MbChr 11: 113.67 – 113.96 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a member of the immunoglobulin superfamily.[7] The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined.[8]

References

Further reading

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