SEC14L1

SEC14-like protein 1 is a protein that in humans is encoded by the SEC14L1 gene.^[5][6]

AliasesSEC14L1, PRELID4A, SEC14L, SEC14 like lipid binding 1

External IDsOMIM: 601504; MGI: 1921386; HomoloGene: 37719; GeneCards: SEC14L1; OMA:SEC14L1 - orthologs

Chr.Chromosome 17 (human)^[1]

End77,217,101 bp^[1]

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SEC14L1
Identifiers
Aliases	SEC14L1, PRELID4A, SEC14L, SEC14 like lipid binding 1
External IDs	OMIM: 601504; MGI: 1921386; HomoloGene: 37719; GeneCards: SEC14L1; OMA:SEC14L1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q25.2-q25.3 Start 77,088,749 bp[1] End 77,217,101 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 E2 Start 117,005,994 bp[2] End 117,050,094 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in dorsal motor nucleus of vagus nerve internal globus pallidus blood inferior olivary nucleus lower lobe of lung right lung pericardium olfactory bulb sperm Skeletal muscle tissue of rectus abdominis Top expressed in submandibular gland superior frontal gyrus neural layer of retina primary visual cortex perirhinal cortex lens granulocyte dorsal striatum molar CA3 field More reference expression data BioGPS n/a
Gene ontology Molecular function RIG-I binding protein binding molecular function regulator Cellular component cytoplasm Golgi apparatus nucleoplasm cytosol Biological process negative regulation of signal transduction innate immune response negative regulation of RIG-I signaling pathway choline transport immune system process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6397 74136 Ensembl ENSG00000129657 ENSMUSG00000020823 UniProt Q92503 A8Y5H7 RefSeq (mRNA) NM_003003 NM_001039573 NM_001143998 NM_001143999 NM_001144001 NM_001204408 NM_001204410 NM_001166506 NM_001166507 NM_028777 NM_001363165 RefSeq (protein) NP_001034662 NP_001137470 NP_001137471 NP_001137473 NP_001191337 NP_001191339 NP_002994 NP_001159978 NP_001159979 NP_083053 NP_001350094 Location (UCSC) Chr 17: 77.09 – 77.22 Mb Chr 11: 117.01 – 117.05 Mb PubMed search [3] [4]
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The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system.^[6]