SEC61G

Mammalian protein found in Homo sapiens From Wikipedia, the free encyclopedia

Protein transport protein Sec61 subunit gamma is a protein that in humans is encoded by the SEC61G gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesSEC61G, SSS1, Sec61 translocon gamma subunit, SEC61 translocon subunit gamma
Quick facts Available structures, PDB ...
SEC61G
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSEC61G, SSS1, Sec61 translocon gamma subunit, SEC61 translocon subunit gamma
External IDsOMIM: 609215; MGI: 1202066; HomoloGene: 40767; GeneCards: SEC61G; OMA:SEC61G - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014302
NM_001012456

NM_001109971
NM_001109972
NM_011343

RefSeq (protein)

NP_001012474
NP_055117

NP_001103441
NP_001103442
NP_035473

Location (UCSC)Chr 7: 54.75 – 54.76 MbChr 11: 16.5 – 16.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The Sec61 complex forms a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified.[7]

References

Further reading

Related Articles

Wikiwand AI