SEPT8

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Septin-8 is a protein that in humans is encoded by the SEPT8 gene.[5][6][7]

Quick facts SEPTIN8, Identifiers ...
SEPTIN8
Identifiers
AliasesSEPTIN8, SEP2, septin 8, SEPT8
External IDsOMIM: 608418; MGI: 894310; HomoloGene: 57205; GeneCards: SEPTIN8; OMA:SEPTIN8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 5: 132.75 – 132.81 MbChr 11: 53.41 – 53.44 Mb
PubMed search[3][4]
Wikidata
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Function

SEPT8 is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking.[7]

Interactions

SEPT8 has been shown to interact with PFTK1[8] and SEPT5.[9][10]

References

Further reading

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