SFXN1

SFXN1
Identifiers
Aliases	SFXN1, TCC, sideroflexin 1, SLC56A1
External IDs	OMIM: 615569; MGI: 2137677; HomoloGene: 41494; GeneCards: SFXN1; OMA:SFXN1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	175,529,742 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	54,262,361 bp
RNA expression pattern
	Top expressed in
	amniotic fluid; ; buccal mucosa cell; ; ventricular zone; ; liver; ; stromal cell of endometrium; ; right lobe of liver; ; ganglionic eminence; ; kidney tubule; ; endothelial cell; ; tendon of biceps brachii;
	Top expressed in
	tunica adventitia of aorta; ; crypt of lieberkuhn of small intestine; ; human kidney; ; brown adipose tissue; ; right kidney; ; lacrimal gland; ; white adipose tissue; ; intestinal villus; ; left lobe of liver; ; parotid gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ion transmembrane transporter activity; L-serine transmembrane transporter activity; D-serine transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; mitochondrion; mitochondrial membranes; integral component of mitochondrial inner membrane; mitochondrial inner membrane;
Biological process	erythrocyte differentiation; ion transmembrane transport; iron ion homeostasis; iron ion transport; ion transport; transmembrane transport; one-carbon metabolic process; L-serine transport; D-serine transport; serine import into mitochondrion; amino acid transport;
	Sources:Amigo / QuickGO
Orthologs
	94081
	14057
	ENSG00000164466
	ENSMUSG00000021474
	Q9H9B4
	Q99JR1
NM_022754; NM_001322977; NM_001322978; NM_001322980; NM_001322981;
	NM_001322982; NM_001322983
	NM_027324
NP_001309906; NP_001309907; NP_001309909; NP_001309910; NP_001309911;
	NP_001309912; NP_073591
	NP_081600
	Wikidata
View/Edit Human	View/Edit Mouse

Sideroflexin-1 is a protein that in humans is encoded by the SFXN1 gene.^[5] According to Nora Kory et al., SFXN1 gene product has mitochondrial serine transporter activity.^[6]