SGSM1

SGSM1
Identifiers
Aliases	SGSM1, RUTBC2, small G protein signaling modulator 1
External IDs	OMIM: 611417; MGI: 107320; HomoloGene: 64485; GeneCards: SGSM1; OMA:SGSM1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	24,927,578 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	113,458,652 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; Brodmann area 23; ; middle temporal gyrus; ; superior frontal gyrus; ; postcentral gyrus; ; entorhinal cortex; ; hypothalamus; ; cerebellar hemisphere; ; primary visual cortex; ; right hemisphere of cerebellum;
	Top expressed in
	superior cervical ganglion; ; arcuate nucleus; ; dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus; ; median eminence; ; lumbar subsegment of spinal cord; ; ventromedial nucleus; ; nucleus of stria terminalis; ; lateral hypothalamus; ; suprachiasmatic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; GTPase activator activity;
Cellular component	Golgi apparatus; membrane; cytoplasm; cytoplasmic vesicle membrane; cytosol; endomembrane system; cytoplasmic vesicle;
Biological process	activation of GTPase activity; intracellular protein transport; regulation of vesicle fusion;
	Sources:Amigo / QuickGO
Orthologs
	129049
	52850
	ENSG00000167037
	ENSMUSG00000042216
	Q2NKQ1
	Q8BPQ7
	NM_133454; NM_001039948; NM_001098497; NM_001098498
	NM_001162965; NM_001254731; NM_172718; NM_001309526; NM_001309528
	NP_001035037; NP_001091967; NP_001091968; NP_597711
	NP_001156437; NP_001241660; NP_001296455; NP_001296457; NP_766306
	Wikidata
View/Edit Human	View/Edit Mouse

Small G protein signaling modulator 1 (SGSM1) also known as RUN and TBC1 domain-containing protein 2 (RUTBC2) and nurr1-interacting protein (NuIP)^[5] is a protein in humans that is encoded by the SGSM1 gene.^[6]^[7]