SH3GL2

SH3GL2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X03, 1X04, 2D4C, 2DBM
Identifiers
Aliases	SH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4, SH3 domain containing GRB2 like 2, endophilin A1
External IDs	OMIM: 604465; MGI: 700009; HomoloGene: 20652; GeneCards: SH3GL2; OMA:SH3GL2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	17,797,124 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	85,557,432 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle temporal gyrus; ; endothelial cell; ; cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; cerebellar vermis; ; primary visual cortex; ; lateral nuclear group of thalamus; ; orbitofrontal cortex;
	Top expressed in
	transitional epithelium of urinary bladder; ; lobe of cerebellum; ; cerebellar vermis; ; pontine nuclei; ; subiculum; ; habenula; ; deep cerebellar nuclei; ; medial vestibular nucleus; ; motor neuron; ; medial dorsal nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; lipid binding; identical protein binding; protein homodimerization activity; protein C-terminus binding; protein kinase binding;
Cellular component	cytoplasm; clathrin-coated endocytic vesicle membrane; membrane; Golgi membrane; plasma membrane; synapse; early endosome; endosome; cytosol; soma; perinuclear region of cytoplasm; basal dendrite; presynapse; synaptic vesicle membrane; photoreceptor ribbon synapse; Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; glutamatergic synapse; presynaptic cytosol;
Biological process	negative regulation of epidermal growth factor receptor signaling pathway; endocytosis; antigen processing and presentation of exogenous peptide antigen via MHC class II; central nervous system development; synaptic vesicle endocytosis; regulation of receptor internalization; signal transduction; membrane organization; synaptic vesicle uncoating; neuron projection development; dendrite extension; cellular response to brain-derived neurotrophic factor stimulus; lipid tube assembly; membrane tubulation; membrane bending; vesicle scission; positive regulation of membrane tubulation; regulation of clathrin-dependent endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	6456
	20404
	ENSG00000107295
	ENSMUSG00000028488
	Q99962
	Q62420
	NM_003026
	NM_019535
	NP_003017
	NP_062408
	Wikidata
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