SKIL

SKIL
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EQ5
Identifiers
Aliases	SKIL, SNO, SnoA, SnoI, SnoN, SKI-like proto-oncogene, SKI like proto-oncogene
External IDs	OMIM: 165340; MGI: 106203; HomoloGene: 3948; GeneCards: SKIL; OMA:SKIL - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	170,396,835 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	31,176,726 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; mucosa of paranasal sinus; ; jejunal mucosa; ; Achilles tendon; ; Skeletal muscle tissue of biceps brachii; ; visceral pleura; ; epithelium of nasopharynx; ; epithelium of colon; ; endothelial cell; ; superficial temporal artery;
	Top expressed in
	molar; ; cumulus cell; ; external carotid artery; ; pineal gland; ; tunica media of zone of aorta; ; ciliary body; ; body of femur; ; mesenteric lymph nodes; ; internal carotid artery; ; umbilical cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription corepressor activity; protein domain specific binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; SMAD binding; chromatin binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein-containing complex binding;
Cellular component	cytoplasm; PML body; nucleoplasm; acrosomal vesicle; nucleus; protein-containing complex;
Biological process	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; response to cytokine; lymphocyte homeostasis; response to antibiotic; negative regulation of transcription by RNA polymerase II; blastocyst formation; positive regulation of axonogenesis; protein homotrimerization; lens fiber cell differentiation; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; spermatogenesis; protein heterotrimerization; response to growth factor; skeletal muscle tissue development; negative regulation of BMP signaling pathway; transforming growth factor beta receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; neuron development; negative regulation of cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	6498
	20482
	ENSG00000136603
	ENSMUSG00000027660
	P12757
	Q60665
	NM_001145097; NM_001145098; NM_001248008; NM_005414
NM_001039090; NM_001271772; NM_011386; NM_001398558; NM_001398559;
	NM_001398560
	NP_001138569; NP_001138570; NP_001234937; NP_005405
NP_001034179; NP_001258701; NP_035516; NP_001385487; NP_001385488;
	NP_001385489
	Wikidata
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