SLA2

SLA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4M4Z
Identifiers
Aliases	SLA2, C20orf156, MARS, SLAP-2, SLAP2, Src-like-adaptor 2, Src like adaptor 2
External IDs	OMIM: 606577; MGI: 1925049; HomoloGene: 49989; GeneCards: SLA2; OMA:SLA2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	36,646,196 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	156,729,112 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; granulocyte; ; monocyte; ; blood; ; testicle; ; lymph node; ; spleen; ; appendix; ; oocyte; ; bone marrow cell;
	Top expressed in
	thymus; ; zygote; ; primary oocyte; ; secondary oocyte; ; granulocyte; ; embryo; ; blood; ; embryo; ; pharynx; ; morula;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; protein N-terminus binding; non-membrane spanning protein tyrosine kinase activity; signaling receptor binding; 1-phosphatidylinositol-3-kinase regulator activity;
Cellular component	cytoplasm; late endosome; plasma membrane; endosome membrane; membrane; cytoplasmic vesicle; nucleoplasm; Golgi apparatus; intracellular membrane-bounded organelle; extrinsic component of cytoplasmic side of plasma membrane; phosphatidylinositol 3-kinase complex;
Biological process	negative regulation of calcium-mediated signaling; negative regulation of B cell activation; intracellular receptor signaling pathway; negative regulation of transcription by RNA polymerase II; T cell activation; B cell mediated immunity; regulation of immune response; antigen receptor-mediated signaling pathway; positive regulation of signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; cell migration; cell differentiation; peptidyl-tyrosine autophosphorylation; regulation of cell population proliferation; innate immune response; regulation of signal transduction; regulation of phosphatidylinositol 3-kinase activity; negative regulation of insulin receptor signaling pathway; phosphatidylinositol phosphate biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	84174
	77799
	ENSG00000101082
	ENSMUSG00000027636
	Q9H6Q3
	Q8R4L0
	NM_032214; NM_175077
	NM_029983; NM_001356495
	NP_115590; NP_778252
	NP_084259; NP_001343424
	Wikidata
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