Neutral amino acid transporter A

SLC1A4
Identifiers
Aliases	SLC1A4, ASCT1, SATT, solute carrier family 1 member 4
External IDs	OMIM: 600229; MGI: 2135601; HomoloGene: 20655; GeneCards: SLC1A4; OMA:SLC1A4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	65,023,865 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	20,282,713 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; sperm; ; glutes; ; spinal ganglia; ; entorhinal cortex; ; internal globus pallidus; ; nucleus accumbens; ; external globus pallidus; ; Skeletal muscle tissue of biceps brachii; ; middle temporal gyrus;
	Top expressed in
	supraoptic nucleus; ; paraventricular nucleus of hypothalamus; ; arcuate nucleus; ; ascending aorta; ; crypt of lieberkuhn of small intestine; ; aortic valve; ; fossa; ; median eminence; ; deep cerebellar nuclei; ; medial vestibular nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	L-glutamine transmembrane transporter activity; L-threonine transmembrane transporter activity; L-proline transmembrane transporter activity; L-serine transmembrane transporter activity; L-hydroxyproline transmembrane transporter activity; L-cystine transmembrane transporter activity; neutral amino acid transmembrane transporter activity; L-alanine transmembrane transporter activity; symporter activity; chloride channel activity; amino acid transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; melanosome; plasma membrane; integral component of plasma membrane; cell surface; soma; dendrite; extracellular exosome; intermediate filament; centrosome; microtubule organizing center;
Biological process	synaptic transmission, glutamatergic; cognition; L-alanine transport; proline transport; hydroxyproline transport; amino acid transport; L-cystine transport; L-serine transport; glutamine transport; threonine transport; chloride transmembrane transport; amino acid transmembrane transport; proline transmembrane transport; transmembrane transport; chloride transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	6509
	55963
	ENSG00000115902
	ENSMUSG00000020142
	P43007
	O35874
	NM_001135581; NM_001193493; NM_003038; NM_001348406; NM_001348407
	NM_018861
	NP_001180422; NP_003029; NP_001335335; NP_001335336
	NP_061349
	Wikidata
View/Edit Human	View/Edit Mouse

Neutral amino acid transporter A is a protein that in humans is encoded by the SLC1A4 gene.^[5]^[6]^[7] In humans, it is expressed in the brain, lung, skeletal muscle, intestine and kidney.^[8]