SLC25A16

Solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 is a protein in humans that is encoded by the SLC25A16 gene. ^[5]

AliasesSLC25A16, D10S105E, GDA, GDC, HGT.1, ML7, hML7, solute carrier family 25 member 16

External IDsOMIM: 139080; MGI: 1920382; HomoloGene: 21858; GeneCards: SLC25A16; OMA:SLC25A16 - orthologs

Chr.Chromosome 10 (human)^[1]

End68,527,523 bp^[1]

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SLC25A16
Identifiers
Aliases	SLC25A16, D10S105E, GDA, GDC, HGT.1, ML7, hML7, solute carrier family 25 member 16
External IDs	OMIM: 139080; MGI: 1920382; HomoloGene: 21858; GeneCards: SLC25A16; OMA:SLC25A16 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q21.3 Start 68,477,998 bp[1] End 68,527,523 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 B4 Start 62,756,412 bp[2] End 62,782,277 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in jejunal mucosa right lobe of liver adipose tissue gonad mammary gland lactiferous gland epithelium of colon lactiferous duct corpus epididymis duodenum Top expressed in left lobe of liver human kidney right kidney Epithelium of choroid plexus parotid gland retinal pigment epithelium lacrimal gland otolith organ utricle seminal vesicula More reference expression data BioGPS n/a
Gene ontology Molecular function antiporter activity secondary active transmembrane transporter activity transmembrane transporter activity Cellular component membrane mitochondrion mitochondrial inner membrane integral component of membrane Biological process transmembrane transport mitochondrial transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8034 73132 Ensembl ENSG00000122912 ENSMUSG00000071253 UniProt P16260 Q8C0K5 RefSeq (mRNA) NM_152707 NM_001324312 NM_001324313 NM_001324314 NM_001324315 NM_001324317 NM_175194 RefSeq (protein) NP_001311241 NP_001311242 NP_001311243 NP_001311244 NP_001311246 NP_689920 NP_780403 Location (UCSC) Chr 10: 68.48 – 68.53 Mb Chr 10: 62.76 – 62.78 Mb PubMed search [3] [4]
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This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008].