SLC25A51
Human gene and protein
From Wikipedia, the free encyclopedia
Solute carrier family 25 member 51, also known as SLC25A51 and MCART1, is a protein which in humans is encoded by the SLC25A51 gene. This gene encodes a mitochondrial NAD+ transporter[1] and is a member of the mitochondrial carrier family of solute carrier proteins.
Structure
The SLC25A51 gene is located on the p arm of chromosome 9 in position 13.2 and spans 24,954 base pairs.[2] The gene produces a 33.7 kDa protein composed of 297 amino acids.[3] This gene has 6 exons and encodes a multi-pass integral membrane protein localized to the mitochondrial inner membrane.[2][3]
Function
Clinical significance
Diseases associated with this gene include urea cycle disorders.[6]