SLC5A4

The low affinity sodium-glucose cotransporter also known as the sodium/glucose cotransporter 3 (SGLT3) or solute carrier family 5 member 4 (SLC5A4) is a protein that in humans is encoded by the SLC5A4 gene.^[5][6][7] It functions as a sugar sensor.

AliasesSLC5A4, DJ90G24.4, SAAT1, SGLT3, solute carrier family 5 member 4

External IDsMGI: 1927848; HomoloGene: 8591; GeneCards: SLC5A4; OMA:SLC5A4 - orthologs

Chr.Chromosome 22 (human)^[1]

End32,255,347 bp^[1]

Quick facts Identifiers, Aliases ...

SLC5A4
Identifiers
Aliases	SLC5A4, DJ90G24.4, SAAT1, SGLT3, solute carrier family 5 member 4
External IDs	MGI: 1927848; HomoloGene: 8591; GeneCards: SLC5A4; OMA:SLC5A4 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q12.3 Start 32,218,464 bp[1] End 32,255,347 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 C1 Start 75,983,285 bp[2] End 76,025,099 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum testicle islet of Langerhans smooth muscle tissue upper lobe of left lung body of uterus sural nerve right lung left lobe of thyroid gland right lobe of thyroid gland Top expressed in morula jejunum intestinal villus duodenum lumbar subsegment of spinal cord proximal tubule cumulus cell ileum right kidney ovary More reference expression data BioGPS n/a
Gene ontology Molecular function glucose:sodium symporter activity transmembrane transporter activity Cellular component integral component of membrane membrane integral component of plasma membrane plasma membrane Biological process ion transport transmembrane transport sodium ion transport glucose transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6527 64452 Ensembl ENSG00000100191 ENSMUSG00000020229 UniProt Q9NY91 Q9ET37 RefSeq (mRNA) NM_014227 NM_133184 RefSeq (protein) NP_055042 NP_573447 Location (UCSC) Chr 22: 32.22 – 32.26 Mb Chr 10: 75.98 – 76.03 Mb PubMed search [3] [4]
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