Cationic amino acid transporter 2

SLC7A2
Identifiers
Aliases	SLC7A2, ATRC2, CAT2, HCAT2, solute carrier family 7 member 2
External IDs	OMIM: 601872; MGI: 99828; HomoloGene: 20659; GeneCards: SLC7A2; OMA:SLC7A2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	17,570,573 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	41,375,345 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; islet of Langerhans; ; right lobe of liver; ; trigeminal ganglion; ; gastrocnemius muscle; ; bronchial epithelial cell; ; retinal pigment epithelium; ; right ovary;
	Top expressed in
	epithelium of lens; ; Dermatocranium; ; membranous bone; ; left lobe of liver; ; mandible; ; maxilla; ; muscle of thigh; ; secondary oocyte; ; islet of Langerhans; ; ciliary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	high-affinity lysine transmembrane transporter activity; low-affinity L-arginine transmembrane transporter activity; L-arginine transmembrane transporter activity; basic amino acid transmembrane transporter activity; high-affinity L-arginine transmembrane transporter activity; high-affinity L-ornithine transmembrane transporter activity; L-ornithine transmembrane transporter activity; L-lysine transmembrane transporter activity; amino acid transmembrane transporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; integral component of plasma membrane; plasma membrane; cell junction;
Biological process	nitric oxide biosynthetic process; cellular amino acid metabolic process; nitric oxide production involved in inflammatory response; regulation of inflammatory response; L-lysine import across plasma membrane; L-arginine import across plasma membrane; L-ornithine import across plasma membrane; macrophage activation; L-ornithine transmembrane transport; amino acid transport; regulation of macrophage activation; transmembrane transport; L-lysine transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	6542
	11988
	ENSG00000003989
	ENSMUSG00000031596
	P52569
	P18581
	NM_001008539; NM_001164771; NM_003046; NM_001370337; NM_001370338
	NM_001044740; NM_007514
	NP_001008539; NP_001158243; NP_003037; NP_001357266; NP_001357267
	NP_001038205; NP_031540
	Wikidata
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