Cationic amino acid transporter 3

Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene.^[5][6]

AliasesSLC7A3, ATRC3, CAT-3, CAT3, solute carrier family 7 member 3

External IDsOMIM: 300443; MGI: 1100521; HomoloGene: 56382; GeneCards: SLC7A3; OMA:SLC7A3 - orthologs

Chr.X chromosome (human)^[1]

End70,931,125 bp^[1]

Quick facts SLC7A3, Identifiers ...

SLC7A3
Identifiers
Aliases	SLC7A3, ATRC3, CAT-3, CAT3, solute carrier family 7 member 3
External IDs	OMIM: 300443; MGI: 1100521; HomoloGene: 56382; GeneCards: SLC7A3; OMA:SLC7A3 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq13.1 Start 70,925,579 bp[1] End 70,931,125 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X C3- D Start 100,122,816 bp[2] End 100,129,626 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tail of epididymis gonad tibialis anterior muscle ventricular zone thymus ganglionic eminence testicle gastric mucosa mucosa of ileum body of uterus Top expressed in epiblast embryo dorsomedial hypothalamic nucleus otic placode ventral tegmental area paraventricular nucleus of hypothalamus central gray substance of midbrain lateral hypothalamus primitive streak ventromedial nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function basic amino acid transmembrane transporter activity L-lysine transmembrane transporter activity amino acid transmembrane transporter activity transmembrane transporter activity L-ornithine transmembrane transporter activity Cellular component integral component of membrane membrane plasma membrane Biological process basic amino acid transmembrane transport L-lysine transmembrane transport L-alpha-amino acid transmembrane transport L-arginine transmembrane transport amino acid transport transmembrane transport L-arginine import across plasma membrane L-ornithine transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84889 11989 Ensembl ENSG00000165349 ENSMUSG00000031297 UniProt Q8WY07 P70423 RefSeq (mRNA) NM_032803 NM_001048164 NM_001301840 NM_007515 RefSeq (protein) NP_001041629 NP_116192 NP_001288769 NP_031541 Location (UCSC) Chr X: 70.93 – 70.93 Mb Chr X: 100.12 – 100.13 Mb PubMed search [3] [4]
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SLC7A3 is a member of the system y+ family of transporters characterized by sodium-independent transport of cationic amino acids.[supplied by OMIM]^[6]