SLITRK2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

SLIT and NTRK-like protein 2 is a protein that in humans is encoded by the SLITRK2 gene.[5][6][7]

AliasesSLITRK2, CXorf2, SLITL1, SLIT and NTRK like family member 2, CXorf1, TMEM257
End145,829,856 bp[1]
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SLITRK2
Identifiers
AliasesSLITRK2, CXorf2, SLITL1, SLIT and NTRK like family member 2, CXorf1, TMEM257
External IDsOMIM: 300561; MGI: 2679449; HomoloGene: 13054; GeneCards: SLITRK2; OMA:SLITRK2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001161431
NM_198863

RefSeq (protein)

NP_001154903
NP_942563

Location (UCSC)Chr X: 145.82 – 145.83 MbChr X: 65.69 – 65.7 Mb
PubMed search[3][4]
Wikidata
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Function

Members of the SLITRK family, such as SLITRK2, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK2, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity.[7][6]

References

Further reading

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