SMPD4

SMPD4
Identifiers
Aliases	SMPD4, NET13, NSMASE-3, NSMASE3, sphingomyelin phosphodiesterase 4, SKNY, NEDMABA, NEDMEBA
External IDs	OMIM: 610457; MGI: 1924876; HomoloGene: 9813; GeneCards: SMPD4; OMA:SMPD4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	130,182,750 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	17,462,692 bp
RNA expression pattern
	Top expressed in
	pituitary gland; ; anterior pituitary; ; right hemisphere of cerebellum; ; left lobe of thyroid gland; ; canal of the cervix; ; right lobe of thyroid gland; ; apex of heart; ; body of uterus; ; right uterine tube; ; left ovary;
	Top expressed in
	tail of embryo; ; otic vesicle; ; genital tubercle; ; otic placode; ; saccule; ; epiblast; ; spermatocyte; ; primary visual cortex; ; superior frontal gyrus; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sphingomyelin phosphodiesterase activity; hydrolase activity; metal ion binding; sphingomyelin phosphodiesterase D activity;
Cellular component	integral component of membrane; Golgi membrane; trans-Golgi network; Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum; membrane;
Biological process	ceramide biosynthetic process; cellular response to tumor necrosis factor; sphingomyelin catabolic process; glycosphingolipid metabolic process; glycerophospholipid catabolic process; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	55627
	77626
	ENSG00000136699
	ENSMUSG00000005899
	Q9NXE4
	Q6ZPR5
	NM_001171083; NM_001171084; NM_017751; NM_017951
	NM_001164609; NM_001164610; NM_001164611; NM_029945
	NP_001164554; NP_060221; NP_060421; NP_060421.2
	NP_001158081; NP_001158082; NP_001158083; NP_084221
	Wikidata
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