SNAP29

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Synaptosomal-associated protein 29 is a protein that in humans is encoded by the SNAP29 gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesSNAP29, CEDNIK, SNAP-29, synaptosome associated protein 29kDa, synaptosome associated protein 29
Quick facts Available structures, PDB ...
SNAP29
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSNAP29, CEDNIK, SNAP-29, synaptosome associated protein 29kDa, synaptosome associated protein 29
External IDsOMIM: 604202; MGI: 1914724; HomoloGene: 3512; GeneCards: SNAP29; OMA:SNAP29 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004782

NM_023348

RefSeq (protein)

NP_004773

NP_075837

Location (UCSC)Chr 22: 20.86 – 20.89 MbChr 16: 17.22 – 17.25 Mb
PubMed search[3][4]
Wikidata
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Function

This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.[7]

Interactions

SNAP29 has been shown to interact with Syntaxin 3[5] and EHD1.[8]

SNAP29 was shown to interact with CVB3 and EV-D68 viral protease 3C.[9][10]

See also

References

Further reading

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