SNTG1

Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene.^[5][6]

AliasesSNTG1, G1SYN, SYN4, syntrophin gamma 1

External IDsOMIM: 608714; MGI: 1918346; HomoloGene: 56834; GeneCards: SNTG1; OMA:SNTG1 - orthologs

Chr.Chromosome 8 (human)^[1]

End50,796,692 bp^[1]

Quick facts Identifiers, Aliases ...

SNTG1
Identifiers
Aliases	SNTG1, G1SYN, SYN4, syntrophin gamma 1
External IDs	OMIM: 608714; MGI: 1918346; HomoloGene: 56834; GeneCards: SNTG1; OMA:SNTG1 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q11.21 Start 49,909,789 bp[1] End 50,796,692 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 A1-A2 Start 8,361,475 bp[2] End 9,299,878 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 primary visual cortex middle temporal gyrus ventricular zone testicle dorsolateral prefrontal cortex Brodmann area 9 nucleus accumbens prefrontal cortex caudate nucleus Top expressed in lumbar subsegment of spinal cord dentate gyrus of hippocampal formation granule cell spermatid primary visual cortex superior frontal gyrus neural layer of retina facial motor nucleus embryo cerebellar cortex hippocampus proper More reference expression data BioGPS More reference expression data
Gene ontology Molecular function actin binding protein C-terminus binding structural molecule activity Cellular component cytoplasm ruffle membrane syntrophin complex cytoskeleton nucleus dystrophin-associated glycoprotein complex Biological process cell communication Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54212 71096 Ensembl ENSG00000147481 ENSMUSG00000025909 UniProt Q9NSN8 Q925E1 RefSeq (mRNA) NM_001287813 NM_001287814 NM_018967 NM_001321773 NM_001321775 NM_001321776 NM_001321777 NM_001321778 NM_001290390 NM_001290392 NM_001290393 NM_027671 RefSeq (protein) NP_001274742 NP_001274743 NP_001308702 NP_001308704 NP_001308705 NP_001308706 NP_001308707 NP_061840 NP_001274742.1 NP_061840.1 NP_001308702.1 NP_001277319 NP_001277321 NP_001277322 NP_081947 Location (UCSC) Chr 8: 49.91 – 50.8 Mb Chr 1: 8.36 – 9.3 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close

The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain. Transcript variants for this gene have been described, but their full-length nature has not been determined.^[6]