SORBS3

SORBS3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CT3, 2DLM, 2NWM, 2YUP
Identifiers
Aliases	SORBS3, SCAM-1, SCAM1, SH3D4, sorbin and SH3 domain containing 3
External IDs	OMIM: 610795; MGI: 700013; HomoloGene: 4218; GeneCards: SORBS3; OMA:SORBS3 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	22,575,788 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	70,449,438 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; right coronary artery; ; popliteal artery; ; tibial arteries; ; tibial nerve; ; gastric mucosa; ; left coronary artery; ; canal of the cervix; ; ascending aorta;
	Top expressed in
	external carotid artery; ; muscle of thigh; ; internal carotid artery; ; genital tubercle; ; retinal pigment epithelium; ; vestibular membrane of cochlear duct; ; ankle; ; right lung; ; right lung lobe; ; choroid plexus of fourth ventricle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	vinculin binding; transcription factor binding; structural constituent of cytoskeleton; protein binding;
Cellular component	cytoplasm; cytosol; cell junction; cytoskeleton; nucleus; focal adhesion;
Biological process	cell-substrate adhesion; cell adhesion; muscle contraction; negative regulation of transcription by RNA polymerase II; positive regulation of stress fiber assembly; positive regulation of cytoskeleton organization; positive regulation of MAPK cascade; actin filament organization;
	Sources:Amigo / QuickGO
Orthologs
	10174
	20410
	ENSG00000120896
	ENSMUSG00000022091
	O60504
	Q9R1Z8
	NM_001018003; NM_005775
	NM_001271407; NM_001271408; NM_001271409; NM_011366
	NP_001018003; NP_005766
	NP_001258336; NP_001258337; NP_001258338; NP_035496
	Wikidata
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