SOX13

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Transcription factor SOX-13 is a protein that in humans is encoded by the SOX13 gene.[5][6]

AliasesSOX13, ICA12, Sox-13, SRY-box 13, SRY-box transcription factor 13
End204,127,743 bp[1]
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SOX13
Identifiers
AliasesSOX13, ICA12, Sox-13, SRY-box 13, SRY-box transcription factor 13
External IDsOMIM: 604748; MGI: 98361; HomoloGene: 4159; GeneCards: SOX13; OMA:SOX13 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005686

NM_011439

RefSeq (protein)

NP_005677

NP_035569

Location (UCSC)Chr 1: 204.07 – 204.13 MbChr 1: 133.31 – 133.35 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12.[6]

In melanocytic cells SOX13 gene expression may be regulated by MITF.[7]

See also

References

Further reading

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