SPNS2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Spinster homolog 2 (Drosophila) is a protein that in humans is encoded by the SPNS2 gene.[5]

AliasesSPNS2, sphingolipid transporter 2, SLC62A2, DFNB115, SLC63A2
End4,539,035 bp[1]
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SPNS2
Identifiers
AliasesSPNS2, sphingolipid transporter 2, SLC62A2, DFNB115, SLC63A2
External IDsOMIM: 612584; MGI: 2384936; HomoloGene: 71040; GeneCards: SPNS2; OMA:SPNS2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001124758

NM_001276383
NM_153060

RefSeq (protein)

NP_001118230

NP_001263312
NP_694700

Location (UCSC)Chr 17: 4.5 – 4.54 MbChr 11: 72.34 – 72.38 Mb
PubMed search[3][4]
Wikidata
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Model organisms

The orthologous protein in zebrafish has been shown to transport sphingosine-1-phosphate (S1P) out of cells during vascular development, and human SPNS2 can transport S1P analogues, including the immunomodulating drug FTY720-P.[6][7]

References

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