SPTB

SPTB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1S35, 3EDU, 3F57, 3KBT, 3KBU, 3LBX
Identifiers
Aliases	SPTB, EL3, HS2, HSPTB1, SPH2, spectrin beta, erythrocytic
External IDs	OMIM: 182870; MGI: 98387; HomoloGene: 295; GeneCards: SPTB; OMA:SPTB - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	64,879,907 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	76,757,321 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; muscle of thigh; ; apex of heart; ; Skeletal muscle tissue of rectus abdominis; ; tibialis anterior muscle; ; triceps brachii muscle; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; glutes; ; right auricle of heart;
	Top expressed in
	muscle of thigh; ; fetal liver hematopoietic progenitor cell; ; epithelium of lens; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; tibiofemoral joint; ; ankle; ; superior frontal gyrus; ; skeletal muscle tissue; ; pontine nuclei;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	actin filament binding; structural constituent of cytoskeleton; protein binding; ankyrin binding; actin binding;
Cellular component	spectrin; intrinsic component of the cytoplasmic side of the plasma membrane; cell surface; cell cortex; actin cytoskeleton; spectrin-associated cytoskeleton; cytoskeleton; cytoplasm; Golgi apparatus; cytosol; protein-containing complex;
Biological process	MAPK cascade; axon guidance; endoplasmic reticulum to Golgi vesicle-mediated transport; actin filament capping; cytoskeleton organization;
	Sources:Amigo / QuickGO
Orthologs
	6710
	20741
	ENSG00000070182
	ENSMUSG00000021061
	P11277
	P15508
	NM_000347; NM_001024858; NM_001355436; NM_001355437
	NM_013675
	NP_001020029; NP_001342365; NP_001342366
	n/a
	Wikidata
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