SSH3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Protein phosphatase Slingshot homolog 3 is an enzyme that in humans is encoded by the SSH3 gene.[5][6]

AliasesSSH3, SSH3L, slingshot protein phosphatase 3
End67,312,607 bp[1]
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SSH3
Identifiers
AliasesSSH3, SSH3L, slingshot protein phosphatase 3
External IDsOMIM: 606780; MGI: 2683546; HomoloGene: 32372; GeneCards: SSH3; OMA:SSH3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017857
NM_018276

NM_198113
NM_001356620
NM_001374687

RefSeq (protein)

NP_060327

NP_932781
NP_001343549

Location (UCSC)Chr 11: 67.3 – 67.31 MbChr 19: 4.31 – 4.32 Mb
PubMed search[3][4]
Wikidata
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Function

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002).[supplied by OMIM][6]

References

Further reading

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