Somatostatin receptor 5

Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene.^[5]

AliasesSSTR5, SS-5-R, Somatostatin receptor 5

External IDsMGI: 894282; HomoloGene: 20287; GeneCards: SSTR5; OMA:SSTR5 - orthologs

Chr.Chromosome 16 (human)^[1]

End1,081,454 bp^[1]

Quick facts SSTR5, Identifiers ...

SSTR5
Identifiers
Aliases	SSTR5, SS-5-R, Somatostatin receptor 5
External IDs	MGI: 894282; HomoloGene: 20287; GeneCards: SSTR5; OMA:SSTR5 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 1,072,747 bp[1] End 1,081,454 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 A3.3|17 12.62 cM Start 25,708,849 bp[2] End 25,716,262 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right auricle of heart apex of heart anterior pituitary right adrenal cortex left ventricle Descending thoracic aorta left adrenal cortex ascending aorta right coronary artery metanephros Top expressed in embryo embryo choroid plexus of fourth ventricle soleus muscle entorhinal cortex superior frontal gyrus primary motor cortex superior colliculus basal forebrain striatum of neuraxis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function neuropeptide binding G protein-coupled receptor activity signal transducer activity somatostatin receptor activity peptide binding Cellular component integral component of membrane neuron projection plasma membrane integral component of plasma membrane membrane Biological process positive regulation of cytokinesis G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger glucose homeostasis signal transduction negative regulation of cell population proliferation regulation of insulin secretion somatostatin signaling pathway chemical synaptic transmission cellular response to glucocorticoid stimulus neuropeptide signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6755 20609 Ensembl ENSG00000162009 ENSMUSG00000050824 UniProt P35346 O08858 RefSeq (mRNA) NM_001053 NM_001172560 NM_001172572 NM_001172573 NM_001191008 NM_011425 RefSeq (protein) NP_001044 NP_001166031 NP_001177937 NP_035555 Location (UCSC) Chr 16: 1.07 – 1.08 Mb Chr 17: 25.71 – 25.72 Mb PubMed search [3] [4]
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Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR5 is a member of the superfamily of receptors having seven transmembrane segments.^[6]