SYTL2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Synaptotagmin-like 2, also known as SYTL2, is a human gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesSYTL2, CHR11SYT, EXO4, PPP1R151, SGA72M, SLP2, SLP2A, synaptotagmin like 2
Quick facts Available structures, PDB ...
SYTL2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSYTL2, CHR11SYT, EXO4, PPP1R151, SGA72M, SLP2, SLP2A, synaptotagmin like 2
External IDsOMIM: 612880; MGI: 1933366; HomoloGene: 131343; GeneCards: SYTL2; OMA:SYTL2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 11: 85.69 – 85.81 MbChr 7: 89.95 – 90.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A), which suggests a role in vesicle trafficking. Multiple alternatively spiced transcript variants encoding distinct isoforms have been observed.[5]

Interactions

SYTL2 has been shown to interact with RAB27A.[6][7][8]

References

Further reading

Related Articles

Wikiwand AI