Sulfoxone

Sulfoxone or aldesulfone sodium is an anti-leprosy drug.^[1] It is also known as diasone. Diasone is mentioned as an anti-leprosy drug in the 1961 movie "The Devil At 4 O'clock". Sulfoxone sodium was introduced in Japan in 1948.^[2] Ernest Muir introduced it to Western use while serving as superintendent of the Chacachacare Leprosarium on Trinidad in the Caribbean.^[3]

Routes of
administrationOral

ATC code

• J04BA03 (WHO)

Protein binding69%

MetabolismHepatic

Quick facts Clinical data, Routes ofadministration ...

Sulfoxone

Clinical data
Routes of administration	Oral
ATC code	J04BA03 (WHO)
Pharmacokinetic data
Protein binding	69%
Metabolism	Hepatic
Elimination half-life	3 to 8 hours
Identifiers
IUPAC name [4-[4-(sulfinomethylamino) phenyl] sulfonylphenyl] aminomethanesulfinic acid
CAS Number	144-75-2 Y
PubChem CID	8954
DrugBank	DB01145 N
ChemSpider	8610 Y
UNII	57OWB0Q221
KEGG	D02521 Y
ChEMBL	ChEMBL1200580 N
CompTox Dashboard (EPA)	DTXSID80162594
Chemical and physical data
Formula	C14H16N2Na2O6S3
Molar mass	450.45 g·mol−1
3D model (JSmol)	Interactive image
SMILES [Na+].[Na+].[O-]S(=O)CNc1ccc(cc1)S(=O)(=O)c2ccc(NCS([O-])=O)cc2
InChI InChI=1S/C14H16N2O6S3.2Na/c17-23(18)9-15-11-1-5-13(6-2-11)25(21,22)14-7-3-12(4-8-14)16-10-24(19)20;;/h1-8,15-16H,9-10H2,(H,17,18)(H,19,20);;/q;2*+1/p-2 Y Key:AZBNFLZFSZDPQF-UHFFFAOYSA-L Y
NY (what is this?)  (verify)

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