Symbescaline
Pharmaceutical compound
From Wikipedia, the free encyclopedia
Symbescaline (SB), also known as 3,5-diethoxy-4-methoxyphenethylamine, is a psychoactive drug of the phenethylamine and scaline families related to mescaline.[1][2][3] It is the analogue of mescaline in which the methoxy groups at the 3 and 5 positions have been replaced with ethoxy groups.[1][2][3] In addition, symbescaline is a positional isomer of asymbescaline.[1][2][3]
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| Other names | SB; 3,5-Diethoxy-4-methoxyphenethylamine |
| Routes of administration | Oral[1] |
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| Duration of action | Unknown[1] |
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| Formula | C13H21NO3 |
| Molar mass | 239.315 g·mol−1 |
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In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists symbescaline's dose as above 240 mg orally and its duration as unknown.[1][2][3] The effects of symbescaline have been reported to include no effects, a vague threshold, a slight chill, and strange and disrupted sleep.[1] It is said to have a very unpleasant taste.[1] Shulgin concluded that symbescaline is "probably not active".[1]
The chemical synthesis of symbescaline has been described.[1]
Symbescaline was first described in the scientific literature by Alexander Shulgin and Peyton Jacob III in 1984.[4] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]